We are actively hiring!

The Mei Laboratory studies the remodeling and regulatory mechanisms of the tumor microenvironment during tumor progression and metastasis. The lab combines single-cell technologies, genomic datasets, machine learning, and experimental methods to investigate how the tumor microenvironment and gene regulatory factors control tumor metastasis cascade. By advancing our understanding of malignant cell heterogeneity and tumor microenvironment remodeling, we aim to drive the development of novel therapeutic approaches for patients with metastatic cancer. The current focuses in lab include the following directions: 1) Developing computational methods for integrating multi-modal data, such as scRNA-seq, scATAC-seq, spatial transcriptomics, ChIP-seq, and CRISPR screening. 2) Investigating context-dependent remodeling of the tumor microenvironment. 3) Identifying novel regulators within the tumor microenvironment. 4) Exploring tumor organ specific metastasis with multi-omics data integration.

Computational Biology Postdoc Position

We are seeking highly motivated postdoctoral fellow to join our team. The successful candidates will collaborate with researchers across multiple institutions. Our lab is primarily affiliated with the Fralin Biomedical Research Institute (FBRI) Cancer Research Center DC of Virginia Tech and jointly we are members of the Children’s National Center for Cancer and Immunology Research. The positions offer annual salary of $65,000~$70,000 and are adjustable based on research experience.

Requirements:

• PhD and/or MD in Data Science, Bioinformatics, Computational Biology, Biology, Statistics, Mathematics, Physics, Computer science or other related fields.

• Experience in high-throughput sequencing data analysis, experience in supervised and unsupervised machine learning, or deep learning models.

• Strong programming skills in Python or R, and Linux Shell; experience in genomics data processing and open source repositories e.g. GitHub is a plus.

• Track record of first/co-first-author original research papers.

• Strong oral and written communication skills.

Interested applicants should submit the following materials via email to Dr. Shenglin Mei (shenglinmei@vtc.vt.edu): 1) a cover letter describing current research activities and your interest in this position, 2) a current CV (including publications), and 3) contact information for three references.

Bioinformatics Research Assistant Position

This position will provide ample opportunities for professional development and the acquisition of cutting-edge skills in basic and translational cancer genomics research, research planning and strategy, and data analysis and interpretation. The successful candidates will collaborate with researchers across multiple institutions.

Requirements:

• Master’s degree in Data Science, Bioinformatics, Computational Biology, Biology, Statistics, Mathematics, Physics, Computer science or other related fields.

• One or more years of research training.

• Some coding knowledge of either R or python.

• The ability to work in teams, excellent communication and data presentation skills

Interested applicants should submit the following materials via email to Dr. Shenglin Mei (shenglinmei@vtc.vt.edu): 1) a cover letter, 2) a current CV (including publications), and 3) contact information for two references.

Expected start date is Jan 2025.